Endothelium vs Epithelium: Spot the Difference


Illustration of key differences between Endothelium vs Epithelium. Epithelium of epithelial cells refers to a broad group of cells that cover body surfaces (skin), line covering of organs (respiratory system, digestive tract, etc.). These cells are involved in protection, adsorption of fluids, and secretion. In contrast, the endothelium forms a single-cell layer that lines blood and lymphatic vessels. Endothelial cells regulate blood flow, tissue homeostasis, the exchange of electrolytes, and vascular function. While epithelial cells can form multiple layers, endothelial cells are always thin and simple to allow efficient transport.

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