Development of Kidney Epithelial Cells.

Visual representation of sequential stages in developing kidney epithelial cells. Kidney epithelial cells develop from pluripotent stem cells that develop into mesoderm and metanephric mesenchyme cells. Further, the cells differentiate into nephron progenitor cells. Progenitor cells have different cell segments (podocytes, glomerulus, proximal tubules, loop of Henle, distal tubules, and collecting ducts. The image illustrates key molecular signalling pathways involved in regulating epithelial polarisation, lumen formation, and tissue organisation.

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